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Inner Ear Pathology for the Cochlear Implant Surgeon

Built from Haynes-Glasscock-Shambaugh Surgery of the Ear, Seventh Edition

What’s inside

6 sections · 111 slides

  1. 01

    Cochlear implantation and the temporal bone

    • Current indications for cochlear implantation
    • Residual hearing and the ageing candidate pool
    • Variability in cochlear implant outcome
    • Human temporal bones as a research resource
    • Processing an implanted temporal bone
    • Limitations of the temporal bone method
    • Debates the histopathology informs
    • Normal and implanted human cochlea compared
    • Normal cochlea in mid-modiolar section
    • Implanted cochlea with fibrosis and new bone

    10 slides

  2. 02

    Anatomy of the inner ear

    • Dimensions of the cochlear duct
    • Clinical use of cochlear duct length
    • Angular insertion depth versus array length
    • Scala tympani morphometry
    • Rosenthal canal and the spiral ganglion neurons
    • The cochlear coordinate system
    • Two versus three dimensional reconstruction
    • Counting spiral ganglion neurons
    • Causes of spiral ganglion neuron loss
    • Approaches to the non-malformed cochlea
    • Anatomy of the round window region
    • Surgical exposure of the round window membrane
    • False membranes and niche contents
    • Round window membrane and adjacent structures
    • Facial recess approach to the round window
    • Structures medial to the round window
    • Trajectory of electrode insertion at the round window
    • The cochlear aqueduct

    18 slides

  3. 03

    Response of the cochlea to implantation

    • Acute insertion trauma
    • Injury to the lateral cochlear wall
    • Injury to the osseous spiral lamina
    • Spiral ligament perforation and osseous spiral lamina fracture
    • Translocated array in the scala vestibuli
    • Trauma pattern by electrode design
    • Intracochlear trauma mapped by electrode style
    • Why long-term histopathology matters
    • New fibrous tissue and bone formation
    • Volume of fibro-osseous tissue after implantation
    • Predictors of tissue formation
    • Electrode length and tissue reaction
    • Electric current and the fibrous sheath
    • Three-dimensional reconstruction of an implanted cochlea
    • Insertion approach and tissue formation
    • Fibro-osseous tissue and the acoustic pathway
    • Trauma, hydrops and new bone in the upper scalae
    • Pathologic change at the cochleostomy site
    • Biocompatible is not bio-inert
    • Cellular components of the foreign body response
    • Platinum and silicone particles in the cochlea
    • Macrophages phagocytosing platinum particles
    • Macrophages in the implanted inner ear
    • Consequences of the foreign body response
    • Effects on hair cells and ganglion cells
    • Effects on the vestibular system

    26 slides

  4. 04

    Intracochlear factors influencing outcome

    • Sources of outcome variability
    • Neuron count and speech perception: earlier studies
    • Neuron count and speech perception: the meta-analysis
    • New techniques for neuron analysis
    • Spiral ganglion neurons plotted in three dimensions
    • Electrical stimulation and neuron survival
    • Imaging as a surrogate for neuron count
    • New bone, fibrosis and speech outcome
    • Translocation with lateral wall damage
    • Vestibular function after implantation
    • Vestibular histopathology after implantation
    • Mechanisms of post-implant hydrops
    • Lateral wall damage as an alternative trigger
    • Vestibular effects: summary and open question

    14 slides

  5. 05

    Special pathologies

    • Requirements for implanting an ear with residual hearing
    • Delayed loss of preserved hearing
    • Proposed mechanisms of delayed hearing loss
    • Causes of labyrinthitis ossificans
    • Pathogenesis of post-meningitic ossification
    • Timing and distribution of ossification
    • Implications for the timing of implantation
    • Neuronal loss after meningitic ossification
    • Labyrinthitis ossificans after temporal bone fracture
    • Otosclerosis reaching implant candidacy
    • Surgical implications of advanced otosclerosis
    • Advanced otosclerosis and the implanted cochlea
    • Otosclerotic bone extending into the scala tympani
    • Round window niche obliterated by otosclerosis
    • Otosclerotic foci beside the labyrinthine facial nerve
    • Facial nerve stimulation: mechanism
    • Facial nerve stimulation: frequency and management
    • Cavitary otosclerosis
    • Temporal bone fracture involving the otic capsule
    • Implantation after temporal bone fracture
    • Vestibular findings after temporal bone fracture
    • Cochlear reimplantation

    22 slides

  6. 06

    Summary

    • Surgical messages from the histopathology
    • Chapter summary
    • References
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    • Haynes-Glasscock-Shambaugh Surgery of the Ear, Seventh Edition
    • Join our WhatsApp groups

    15 slides