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Chronic Ear Disease and Cholesteatoma

Built from Haynes-Glasscock-Shambaugh Surgery of the Ear, Seventh Edition

What’s inside

13 sections · 144 slides

  1. 01

    Overview

    • Scope of this topic

    1 slide

  2. 02

    Defining chronic ear disease

    • Definition of chronic ear disease
    • Hallmarks of the chronic ear
    • Overlapping spectrum of chronic ear disease
    • Otitis media and the ex vacuo theory
    • Ex vacuo sequence of middle ear disease
    • Temporal classification of otitis media

    6 slides

  3. 03

    Otitis media with an intact tympanic membrane

    • Eustachian tube dilatory dysfunction
    • Otitis media with effusion
    • Mucosal changes in otitis media with effusion
    • Acute otitis media
    • Phases of acute otitis media
    • Otoscopy of otitis media with an intact drum

    6 slides

  4. 04

    Chronic suppurative otitis media

    • Natural history of an acute perforation
    • Definition of chronic suppurative otitis media
    • Otoscopy of chronic suppurative otitis media
    • Histopathology of chronic suppurative otitis media
    • Remodelling of the middle ear cleft
    • Antimicrobial therapy and long-term relapse
    • Biofilm persister cells and antibiotic failure
    • Traditional subtypes of chronic otitis media
    • Limitations of the tubotympanic classification
    • Severity grading of chronic ear disease
    • Middle ear risk index
    • Middle ear risk index (continued)
    • Middle ear risk index (continued)

    13 slides

  5. 05

    Tympanic membrane atelectasis

    • Pathogenesis of tympanic membrane atelectasis
    • Consequences of the dimeric drumhead
    • Atelectasis with a ventilated middle ear
    • Selective epitympanic dysventilation
    • Isolated epitympanic retraction and opacification
    • Mucosal traction as an alternative mechanism
    • Classification of retraction pockets
    • Classification of tympanic membrane retractions
    • Black classification of eardrum collapse

    9 slides

  6. 06

    Risk factors

    • Evidence base for risk factors
    • Age and Eustachian tube anatomy
    • Host and environmental risk factors
    • Populations at high risk

    4 slides

  7. 07

    Cholesteatoma

    • Definition and structure of cholesteatoma
    • Matrix and perimatrix
    • Cholesteatoma matrix and perimatrix on histology
    • Immunogenicity of cholesteatoma keratin
    • Aural polyp arising from cholesteatoma
    • Absorptive osteitis and bone destruction
    • Effect of bacterial superinfection
    • EAONO/JOS 2017 consensus
    • EAONO/JOS 2017 classification and staging of cholesteatoma
    • EAONO/JOS 2017 classification and staging of cholesteatoma (continued)
    • Congenital cholesteatoma
    • Diagnostic criteria for congenital cholesteatoma
    • Origin theories for congenital cholesteatoma
    • Theories of acquired cholesteatoma
    • Retraction pocket and proliferation theories
    • Immigration theory and non-retraction cholesteatoma
    • Squamous ingrowth at a pars tensa perforation
    • Metaplasia, traction and implantation

    18 slides

  8. 08

    Spread of cholesteatoma in the temporal bone

    • Sites of origin of retraction pocket cholesteatoma
    • Sites of origin of cholesteatoma on the drum
    • Determinants of spread in the temporal bone
    • STAM subsites of the tympanomastoid space
    • STAM subsites of tympanomastoid involvement
    • EAONO/JOS staging of cholesteatoma
    • Pars flaccida cholesteatoma: primary route
    • Inferior extension of pars flaccida disease
    • Pars flaccida cholesteatoma, pattern of spread
    • Pars flaccida cholesteatoma, later stages of spread
    • Anterior pars flaccida cholesteatoma
    • Pars tensa cholesteatoma: routes of spread
    • Pars tensa cholesteatoma, pattern of spread
    • Prognostic contrast between the two types

    14 slides

  9. 09

    Microbiology and biofilms

    • Limitations of culture and PCR
    • Organisms cultured in chronic ear disease
    • Less common bacterial isolates
    • Nasopharynx as a proposed reservoir
    • Fungal infection of the chronic ear
    • Tuberculous otitis
    • Otoscopic features and treatment of tuberculous otitis
    • Biofilms in chronic ear disease
    • Mechanisms of biofilm antibiotic resistance
    • Implication of biofilms for treatment

    10 slides

  10. 10

    Management of chronic suppurative otitis media

    • General scheme of management
    • Basic medical treatment
    • Choice of ototopical agent and ototoxicity
    • Response patterns and complication risk
    • Indications for surgery in chronic otitis media
    • Tympanic membrane repair as mainstay
    • Traditional rationale for mastoidectomy
    • Evidence against routine mastoidectomy
    • Systematic review of therapeutic mastoidectomy
    • Limitations of the outcome literature
    • Selective indications for mastoidectomy
    • Blind sac closure and subtotal petrosectomy
    • Hearing rehabilitation after canal closure

    13 slides

  11. 11

    Negative middle ear pressure and atelectasis

    • Role of Eustachian tube dysfunction
    • Rhinologic medical management
    • Agents of uncertain or no benefit
    • Surgical promotion of middle ear ventilation
    • Tympanostomy in the chronic ear
    • Surgical decision-making in atelectasis
    • Mastoidectomy for negative middle ear pressure
    • Evidence for the pressure buffer concept

    8 slides

  12. 12

    Management of cholesteatoma

    • Indication and goals of cholesteatoma surgery
    • Lifestyle considerations in cholesteatoma surgery
    • Canal wall-up and combined approach surgery
    • Canal wall-down surgery
    • Hybrid procedures
    • Excision versus exteriorisation of the sac
    • Sites of residual and recurrent disease
    • Strategies to reduce residual disease
    • Strategies for lowering cholesteatoma recidivism

    9 slides

  13. 13

    Special situations

    • Suspecting underlying systemic disease
    • Additional workup in refractory disease
    • Eosinophilic otitis media
    • Pathogenesis and management of eosinophilic otitis media
    • Granular myringitis
    • Granular myringitis and canal epithelitis
    • Epithelial migration and the role of the malleus
    • Consequences of an absent malleus
    • Treatment of myringitis
    • Summary of key principles
    • References
    • References (continued)
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    • References (continued)
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    • References (continued)
    • References (continued)
    • References (continued)
    • References (continued)
    • Haynes-Glasscock-Shambaugh Surgery of the Ear, Seventh Edition
    • Join our WhatsApp groups

    21 slides