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Ophthalmology

Extraocular Muscle Structure, Embryology and Ocular Motor Control

Built from Strabismus Simplified, Second Edition

What’s inside

6 sections · 79 slides

  1. 01

    Overview

    • Scope of this topic

    1 slide

  2. 02

    Histopathology of extraocular muscles

    • Extraocular muscle as striated muscle
    • Connective tissue sheaths of the muscle
    • Structure of the muscle fibre
    • The sarcomere
    • Sarcomere structure and changes after contraction
    • Sliding filament mechanism of contraction
    • Excitation-contraction coupling
    • Energy supply for contraction
    • Singly versus multiply innervated fibres
    • Classification of skeletal muscle fibres
    • Functional demands on the extraocular muscles
    • Basis of extraocular muscle fibre classification
    • Orbital and global layers of extraocular muscle
    • Orbital singly innervated fibre
    • Orbital multiply innervated fibre
    • Global red singly innervated fibre
    • Global intermediate singly innervated fibre
    • Global white singly innervated fibre
    • Global multiply innervated fibre
    • Functional properties of extraocular muscle fibre types
    • Fibre type properties at a glance
    • The older Fibrillenstruktur and Felderstruktur classification
    • Fine structure of the levator palpebrae superioris

    23 slides

  3. 03

    Embryological development

    • Origin of the extraocular muscles
    • Timing of extraocular muscle differentiation
    • Waves of myogenesis
    • Critical period and anomalous innervation
    • Postnatal maturation and botulinum toxin
    • Extraocular muscle pulleys

    6 slides

  4. 04

    Accommodation and convergence

    • The near vision complex
    • Accommodative convergence and the AC/A ratio
    • Convergence demand at one metre
    • The metre angle
    • Amplitude of accommodation and the near point
    • Near point of convergence
    • Types of convergence
    • Tonic convergence
    • Proximal convergence
    • Fusional convergence
    • Accommodative convergence
    • Relative convergence and relative accommodation
    • Stimulus versus response AC/A ratio
    • Agents that change the AC/A ratio
    • Accommodative esotropia with a normal AC/A ratio
    • Accommodative esotropia with a high AC/A ratio
    • Miotics, glasses, prisms and surgery compared
    • Methods of estimating the AC/A ratio
    • Heterophoria method
    • Gradient method at 6 metres with concave lenses
    • Gradient method at 33 cm with convex lenses
    • Graphic method
    • Fixation disparity method
    • Clinical uses of the AC/A ratio

    24 slides

  5. 05

    Types of eye movements

    • The six classes of eye movement
    • Purposes of the eye movement systems
    • Comparison of saccades, pursuit, vergence and reflex movements
    • Eye movement characteristics
    • Neural pathways of horizontal and vertical gaze

    5 slides

  6. 06

    Relevant neuroanatomy

    • Scope of the neuroanatomy covered
    • Cortical control of eye movements
    • Brainstem pathways for horizontal and vertical gaze
    • Monocular elevator paresis and vertical gaze centres
    • Reflex and vergence centres
    • Organisation of the oculomotor nucleus
    • Clinical rules for nuclear oculomotor lesions
    • Trochlear nucleus and nerve
    • Abducens nucleus and its position
    • Cell populations of the abducens nucleus
    • Internuclear ophthalmoplegia
    • Summary of key points
    • Suggested reading
    • Suggested reading (continued)
    • Strabismus Simplified

    15 slides