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Paediatric Surgery

Renal Calculus Disease

Built from Puri — Pediatric Surgery and Pediatric Urology

What’s inside

10 sections · 60 slides

  1. 01

    Overview

    • What this talk will teach you

    1 slide

  2. 02

    The Basics

    What a kidney stone is, and why children are different

    • What is renal calculus disease?
    • The headline numbers
    • Why the number of paediatric stones is climbing
    • Second reason: chronic-illness survival

    4 slides

  3. 03

    Who Gets Stones

    Epidemiology: sex, race, climate and geography

    • Why children form fewer stones than adults
    • Sex: the adult male pattern breaks down in children
    • Race and geography shape stone risk
    • Reported incidence varies widely by country

    4 slides

  4. 04

    How Children Present

    Clinical features and differential diagnosis

    • Presenting symptoms depend heavily on age
    • Sorting a stone from its mimics

    2 slides

  5. 05

    Working It Up

    Diagnostic evaluation and imaging

    • The core principle: look for WHY the stone formed
    • Initial evaluation of a child with urolithiasis
    • Reading the urine pH – a free clue to stone type
    • Normal urinary excretion of metabolites (timed)
    • Imaging of the urinary tract for stones
    • Imaging strategy: minimise radiation

    6 slides

  6. 06

    Why Stones Form: Etiology

    Metabolic, structural and infectious causes

    • Three broad categories of cause
    • Stone composition in children
    • Hypercalciuria – too much calcium in the urine
    • Hyperoxaluria – too much oxalate
    • Hyperuricosuria – too much uric acid
    • Cystinuria – an inherited transport defect
    • Hypocitraturia – too little stone blocker
    • Metabolic causes of paediatric urolithiasis – a summary
    • Structural causes – urine that stagnates
    • Infection – both a cause and a consequence

    10 slides

  7. 07

    How Stones Actually Form

    Pathogenesis and genetics

    • Starting conditions: concentrated, low-volume urine
    • Randall’s plaques and the vascular theory
    • A growing genetic story

    3 slides

  8. 08

    Managing the Acute Stone

    Pain, obstruction and surgical options

    • First priorities in an acute stone episode
    • Will the stone pass by itself?
    • Medical expulsive therapy (MET) – helping a stone pass
    • Surgical options by stone size and situation
    • Choosing a surgical approach – the practical rules

    5 slides

  9. 09

    Preventing the Next Stone

    Diet, drugs and surveillance

    • Prevention starts with fluid and diet – for everyone
    • Targeted preventive therapy by metabolic abnormality
    • Why these particular drugs?
    • Surveillance – catching recurrence early

    4 slides

  10. 10

    Outcomes & The Future

    Prognosis and open questions

    • What happens over time
    • Long-term outcomes
    • Future directions – the open questions
    • An 8-year-old passes a calcium oxalate stone. What does the work-up most often reveal, and what is first-line prevention?
    • Key takeaways
    • References (1/5)
    • References (2/5)
    • References (3/5)
    • References (4/5)
    • References (5/5)
    • Pediatric Surgery and Pediatric Urology

    11 slides