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General Surgery

Laparoscopic Staging and Approaches to Cancer

Built from Maingot's Abdominal Operations

What’s inside

9 sections · 183 slides

  1. 01

    Rationale for laparoscopic staging

    What the procedure is, and the gap in imaging it fills

    • Definition of laparoscopic staging
    • Cancers assessed by laparoscopic staging
    • Aims of a staging procedure
    • Limits of noninvasive imaging
    • What laparoscopy adds to imaging
    • Laparoscopic staging alongside other modalities
    • Effect of a positive laparoscopy on care

    7 slides

  2. 02

    Technique of laparoscopic staging

    Access, the systematic survey, washings and ultrasound

    • Timing and setting of the procedure
    • Anaesthesia and patient positioning
    • Equipment for laparoscopic staging
    • Access to the peritoneal cavity
    • Access after previous abdominal surgery
    • Establishing pneumoperitoneum
    • Port placement for staging laparoscopy
    • Sequence of the peritoneal survey
    • Examination of the liver
    • Indirect palpation of the liver surface
    • Biopsy of a suspicious liver lesion
    • Electrosurgical coupling injuries
    • Examination of the porta hepatis
    • Assessment of the duodenum and bile duct
    • Inspection of the transverse mesocolon
    • Tumour infiltration of the colonic mesocolon
    • Entering the lesser sac
    • Incision of the omentum to enter the lesser sac
    • The gastric pillar and coeliac axis
    • Hepatic artery and gastric pillar in the lesser sac
    • Peritoneal lavage cytology
    • Working with the cytologist
    • Rationale for laparoscopic ultrasound
    • Laparoscopic ultrasound probes
    • Scanning the liver with ultrasound
    • Superficial liver metastasis on ultrasound
    • Ultrasound of the biliary tree and pancreas
    • Retropancreatic structures on laparoscopic ultrasound

    28 slides

  3. 03

    Oesophageal carcinoma

    Where imaging stops and laparoscopy starts

    • Burden and outlook in oesophageal cancer
    • Diagnostic modalities for staging oesophagogastric cancers
    • Comparative roles of EUS, CT and FDG-PET
    • Endoscopy and endoscopic palliation
    • Multislice CT for oesophageal staging
    • Endoscopic ultrasonography for TNM staging
    • Accuracy and cost of EUS with fine-needle aspiration
    • Uptake of EUS-FNA in practice
    • FDG-PET and the primary tumour
    • Uptake value and depth of tumour invasion
    • FDG-PET after chemoradiotherapy
    • FDG-PET for metastases and restaging
    • FDG-PET/CT for radiotherapy planning
    • Occult disease remaining after imaging
    • Value of laparoscopy in oesophageal cancer
    • Laparoscopy compared with endoscopic ultrasound
    • The largest staging laparoscopy series
    • Tumour site and yield of laparoscopy
    • Explanation for the site effect
    • Adding laparoscopic ultrasound in oesophagogastric cancer
    • Combined endoscopic and laparoscopic ultrasound
    • Yield by histology and the authors' recommendation

    22 slides

  4. 04

    Gastric cancer

    Occult peritoneal disease, and what the washings say

    • Changing epidemiology of gastric cancer
    • Outcome and the reasons for it
    • Staging tools in gastric cancer
    • Treatment algorithm for gastric cancer
    • Yield of laparoscopy in gastric cancer
    • Accuracy of nodal and T staging
    • Peritoneal metastasis in gastric cancer
    • Diagnostic performance of staging laparoscopy
    • Upstaging and change of treatment plan
    • Limits of modern CT for peritoneal disease
    • Positive peritoneal cytology as a prognostic marker
    • Cytology conversion after chemotherapy
    • Cytology as an independent predictor of death
    • Combining peritoneal deposits with cytology
    • Newcastle disease virus for free cancer cells
    • Sensitivity of the virus method by stage
    • Laparoscopy in early gastric cancer

    17 slides

  5. 05

    Liver and gallbladder cancer

    Selecting who benefits, with a clinical risk score

    • What makes liver disease unresectable
    • Rationale for laparoscopy before liver resection
    • Memorial Sloan-Kettering experience
    • Comparison with straight-to-laparotomy patients
    • Larger follow-up analysis
    • Clinical risk score for resectability in hepatic colorectal disease
    • Using the clinical risk score
    • Validation of the clinical risk score
    • Staging after previous colectomy
    • Adding intraoperative and laparoscopic ultrasound
    • Isolated liver metastasis on laparoscopic ultrasound
    • Ultrasound-guided biopsy of liver lesions
    • Clinical impact of ultrasound-guided biopsy
    • Ultrasound compared with MRI for resectability
    • Hepatocellular carcinoma
    • Laparoscopy as a treatment platform in liver cancer
    • Ultrasound and ablation in cirrhosis
    • Noncolorectal, nonneuroendocrine liver metastases
    • Gallbladder and biliary cancer

    19 slides

  6. 06

    Pancreas cancer

    The largest evidence base, and the sharpest disagreement

    • Outlook in pancreatic adenocarcinoma
    • Rationale for laparoscopic staging in pancreatic cancer
    • Gains from avoiding an unnecessary laparotomy
    • Origins of laparoscopic staging
    • “
    • Quality of the preoperative CT scan
    • Effect on resectability rates
    • Criteria for unresectability at laparoscopy
    • Hepatic metastases from pancreatic cancer
    • Venous involvement and resectability
    • Outcome of the Memorial Sloan-Kettering series
    • Contemporary yield of staging laparoscopy
    • Doran periampullary series
    • Detection of intraabdominal metastases at laparoscopy
    • Carbohydrate antigen 19-9 as a selection tool
    • Optimal CA 19-9 cut-off
    • Treatment algorithm for pancreas cancer
    • Population-based evidence for selective use
    • Adding laparoscopic ultrasound in pancreatic cancer
    • Where ultrasound changes the plan
    • Resection rates with and without ultrasound
    • Coeliac axis and splenic artery infiltration on ultrasound
    • Grading vascular involvement on CT
    • Meta-analysis of laparoscopy and ultrasound
    • Peritoneal cytology in pancreatic cancer
    • Predictive value of positive peritoneal cytology
    • Molecular detection in peritoneal washings
    • Arguments against routine laparoscopy
    • Selective strategies in current practice
    • Laparoscopy in locally advanced disease
    • Further series in locally advanced disease
    • Nonductal and periampullary tumours

    32 slides

  7. 07

    Complications and port-site recurrence

    How safe the procedure is, and what a port-site implant means

    • Safety of staging laparoscopy
    • Early concern about port-site implants
    • Reported port-site recurrence rates
    • Comparison with open wound recurrence
    • What a port-site recurrence signifies
    • Proposed mechanisms of port-site implantation

    6 slides

  8. 08

    Laparoscopic biliary and gastric bypass

    Palliating jaundice and gastric outlet obstruction

    • Need for palliation in pancreatic cancer
    • Choice of biliary bypass
    • Laparoscopic cholecystojejunostomy
    • Selecting patients for cholecystojejunostomy
    • When cholecystojejunostomy is not possible
    • Early laparoscopic palliation series
    • Laparoscopic compared with open palliation
    • Comparative data on gastrojejunostomy
    • Single-incision gastrojejunostomy
    • Incidence of gastric outlet obstruction
    • Delayed gastric emptying without obstruction
    • Need for later bypass after staging laparoscopy
    • Positioning and ports for bypass
    • Bringing the jejunal loop to the gallbladder
    • Jejunal loop brought up to the gallbladder
    • Approximating bowel to gallbladder
    • Making the enterotomies
    • Creating the enterotomies for the anastomosis
    • Firing the linear stapler
    • Stapled cholecystojejunal anastomosis
    • Checking and closing the anastomosis
    • Intracorporeal closure of the enterotomy
    • Hand-sewn and assisted alternatives
    • Result of the assisted technique
    • Technique for gastrojejunostomy
    • Creating and closing the gastrojejunal anastomosis
    • Completed laparoscopic gastrojejunostomy
    • Goals of a palliative procedure

    28 slides

  9. 09

    Summary and references

    Where laparoscopic staging stands today

    • Summary of the role of laparoscopy
    • Points to carry away
    • References
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    • Maingot's Abdominal Operations, 12th Edition

    24 slides