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Radiology

Pulmonary Scintigraphy

Built from Fundamentals of Diagnostic Radiology

What’s inside

8 sections · 98 slides

  1. 01

    Overview

    • What a lung scan does
    • Pulmonary scintigraphy roadmap

    2 slides

  2. 02

    Anatomy and Physiology

    Segmental anatomy, collateral ventilation, and gravity gradients

    • Segmental anatomy of the lungs
    • Pulmonary segment anatomy
    • Collateral ventilation pathways
    • Gravity and ventilation
    • Position and perfusion
    • Ventilation–perfusion matching
    • V/Q mismatch — hallmark of PE

    7 slides

  3. 03

    Ventilation Lung Scan

    Radioactive gases and aerosols map regional airflow

    • Ventilation agents at a glance
    • Xenon-133
    • Xenon-127
    • Krypton-81m
    • Tc-99m aerosols
    • Aerosol particle deposition
    • Aerosol clearance and dosimetry
    • Gas delivery and safety
    • Xenon-133 ventilation technique
    • Three phases of xenon ventilation
    • Washout and positioning
    • Kr-81m and aerosol technique
    • Aerosol dosing order

    13 slides

  4. 04

    Perfusion Lung Scan

    Capillary blockade maps regional blood flow

    • Capillary blockade principle
    • How perfusion scanning works
    • Tc-99m MAA
    • MAA clearance and dose
    • Reduced-particle patients
    • Perfusion dosimetry
    • Injection technique
    • Imaging positions

    8 slides

  5. 05

    V/Q Scans

    Indications, normal patterns, and abnormal findings

    • Indications
    • CTA versus V/Q scan
    • CT pulmonary angiogram with MDCT
    • Pregnancy imaging choice
    • Breast radiation dose
    • Normal ventilation scan
    • Normal perfusion scan
    • Normal V/Q scan
    • Mediastinal effects on perfusion
    • Abnormal scans
    • Abnormal ventilation

    11 slides

  6. 06

    Pulmonary Embolism

    Clinical features, risk factors, and imaging findings

    • PE epidemiology and risk
    • Where emboli come from
    • Clinical presentation
    • CXR findings of PE
    • CT and MRI for PE
    • Acute PE on CTA
    • CT venography for DVT

    7 slides

  7. 07

    V/Q Scan Interpretation

    Defects, diagnostic criteria, and probability

    • Classic PE pattern
    • High-probability V/Q scan
    • Analyzing defects
    • Sizing segmental defects
    • Matched versus mismatched defects
    • Two perfusion defect patterns
    • Nonsegmental defects
    • Low-probability perfusion with pleural effusions
    • Diagnostic criteria
    • Amended PIOPED criteria
    • Intermediate-probability V/Q scan
    • Stripe sign
    • Fissure sign
    • PIOPED study results
    • High-probability predictive value
    • Negative predictive value
    • Clinical assessment matters
    • Wells criteria for PE
    • Combining scan and clinical suspicion
    • Intermediate-probability next steps
    • Intermediate-probability mismatched defects
    • Confirming with angiography
    • V/Q SPECT and low-dose CT
    • Low-dose CT benefits
    • High-probability V/Q with SPECT
    • Follow-up after anticoagulation
    • Early follow-up scans
    • Recurrent pulmonary emboli on serial V/Q
    • Recurrent pulmonary emboli — follow-up perfusion
    • False-positive V/Q scans
    • False-negative V/Q scans

    31 slides

  8. 08

    Nonthromboembolic Pulmonary Disease

    Asthma, COPD, tumors, inflammation, and inhalation injury

    • Asthma
    • Lung neoplasms
    • Quantitative perfusion lung scan
    • Quantitative perfusion lung scan
    • Quantitative ventilation and perfusion
    • COPD ventilation
    • COPD perfusion
    • COPD with matched V/Q defects
    • COPD ventilation and perfusion
    • Inflammatory and infectious disease
    • Aerosol clearance in inflammation
    • Smoke inhalation
    • Key takeaways
    • Suggested Readings
    • Suggested Readings (continued)
    • Suggested Readings (continued)
    • Suggested Readings (continued)
    • Suggested Readings (continued)
    • Brant and Helms' Fundamentals of Diagnostic Radiology

    19 slides