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Radiology

Normal Anatomy and Histopathology

Built from Fundamentals of Diagnostic Radiology

What’s inside

12 sections · 98 slides

  1. 01

    Overview

    Why normal anatomy matters, and the superficial-to-deep road map

    • Why normal anatomy matters
    • Breast layers, superficial to deep
    • Normal mammogram: standard views

    3 slides

  2. 02

    Skin

    Normal thickness, when it thickens, and skin findings that mimic a mass

    • Skin thickness
    • Skin thickness: normal, inflammatory, and retracted
    • Skin glands and cysts
    • Sebaceous cyst on ultrasound
    • Skin lesions as pseudo masses
    • Nevus simulating a breast mass

    6 slides

  3. 03

    Nipple-Areolar Complex

    Anatomy, normal variation, and the imaging appearance of the nipple

    • Nipple-areolar complex anatomy
    • Normal nipple variation
    • Normal nipple appearances
    • Pathologic nipple retraction
    • Nipple simulating a mass
    • Nipple on ultrasound
    • Nipple on ultrasound
    • Nipple on MRI and innervation
    • Nipples on MRI
    • Paget disease of the nipple

    10 slides

  4. 04

    Subcutaneous Tissue

    Cooper ligaments, fat, and how their distortion signals disease

    • Cooper ligaments
    • Cooper ligaments on mammography
    • Cooper ligament distortion
    • Straightening of Cooper ligaments
    • Adipose tissue amount
    • Fat on imaging
    • Fat on mammography and ultrasound

    7 slides

  5. 05

    Milk Ducts and Lobules

    The branching ductal tree, lobules, TDLU, and common cysts

    • Glandular tissue and ducts
    • Ductal and lobular anatomy
    • From duct to alveolus
    • Ductal system on galactography
    • Normal galactogram
    • DCIS in segmental distribution
    • Lobules and the TDLU
    • Histopathology of the normal TDLU
    • Cysts and fibrocystic change

    9 slides

  6. 06

    Stroma

    Breast density, quadrant distribution, interfaces, and symmetry

    • Breast density
    • Quadrant distribution
    • Lower inner quadrant and retromammary fat
    • Fat-glandular interface
    • Normal fat-glandular interface
    • Mass bulging the fat-glandular interface
    • Breast symmetry
    • Asymmetric breast size
    • Shrinking breast from invasive lobular carcinoma

    9 slides

  7. 07

    Chest Wall and Male Breast

    Pectoralis landmarks, muscle invasion, and the rudimentary male breast

    • Chest wall anatomy
    • Pectoralis major and minor muscles
    • Muscle invasion
    • Male breast

    4 slides

  8. 08

    Lymphatics

    Drainage pathways, node levels, and the imaging features of a suspicious node

    • Why lymphatics matter
    • Normal axillary node
    • Normal axillary lymph node
    • Cortical thickness rules
    • Suspicious lymph nodes on ultrasound
    • Node blood supply
    • Change over time
    • Suspicious lymph node features
    • Drainage pathways
    • Lymph node locations
    • Axillary node levels
    • Lymph node levels of the axilla
    • Axillary nodes on MLO
    • Lymph nodes on MLO mammogram
    • Abnormal nodes workup
    • Intramammary nodes
    • Normal intramammary node

    17 slides

  9. 09

    Blood Supply

    Arteries, veins, and Mondor disease

    • Arterial supply
    • Blood supply of the breast on MRI
    • Venous drainage and Mondor disease
    • Mondor thrombophlebitis

    4 slides

  10. 10

    Embryology and Development

    The milk streak, accessory tissue, and how the breast forms over a lifetime

    • The milk streak
    • The milk streak in embryology
    • Accessory breast tissue
    • Accessory breast tissue in the axilla
    • Anomalies terminology
    • Developmental anomalies of the breast
    • Breast development timeline
    • Thelarche and the breast bud
    • Breast bud on ultrasound

    9 slides

  11. 11

    Changes Over Time

    Pregnancy, lactation, and menopause

    • Pregnancy and lactation
    • Lactational changes on mammography
    • Lactation on ultrasound and MRI
    • Menopause

    4 slides

  12. 12

    Pathophysiology of Breast Cancer

    From DNA mutation through DCIS to invasive ductal and lobular carcinoma

    • Breast cancer burden
    • DNA mutations leading to malignancy
    • Progression to invasive disease
    • Ductal carcinoma in situ
    • DCIS: duct cartoon and histopathology
    • Mammographic appearance of DCIS
    • Invasive ductal carcinoma
    • Invasive ductal carcinoma on mammography and ultrasound
    • Invasive lobular carcinoma
    • Invasive lobular carcinoma as architectural distortion
    • Breast cancer types
    • Lobular carcinoma in situ
    • Key takeaways
    • Suggested readings
    • Suggested readings
    • Brant and Helms' Fundamentals of Diagnostic Radiology

    16 slides