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Radiology

Metabolic Bone Disease

Built from Fundamentals of Diagnostic Radiology

What’s inside

5 sections · 75 slides

  1. 01

    Overview

    • Metabolic bone disease overview

    1 slide

  2. 02

    Diminished bone density

    Osteoporosis, disuse osteoporosis, osteomalacia and rickets

    • Osteoporosis versus osteomalacia
    • The film cannot tell them apart
    • Primary versus secondary osteoporosis
    • Cortical thinning on radiographs
    • Normal metacarpal cortical width
    • Osteoporotic metacarpal cortical narrowing
    • DXA measures bone mineral
    • Managing osteoporosis
    • Disuse osteoporosis
    • How disuse thins bone
    • Disuse osteoporosis of the proximal femur
    • Aggressive osteoporosis mimics a tumor
    • Aggressive osteoporosis mimicking a permeative process
    • Solid versus riddled cortex
    • True versus pseudopermeative process (schematic)
    • True permeative differential
    • Myeloma as a true permeative process
    • Pseudopermeative causes
    • Hemangioma causing a pseudopermeative pattern
    • Radiation change as a pseudopermeative pattern
    • Differential diagnosis of pseudopermeative pattern
    • Osteomalacia and Looser fractures
    • Looser fractures in osteomalacia
    • Rickets in children
    • Rickets with frayed physes and bowing

    25 slides

  3. 03

    Parathyroid disorders

    Hyperparathyroidism, hypoparathyroidism and the pseudohypoparathyroid look-alikes

    • Hyperparathyroidism basics
    • Two forms of hyperparathyroidism
    • Subperiosteal resorption
    • Subperiosteal resorption in hyperparathyroidism
    • Sacroiliac changes in hyperparathyroidism
    • Other HPT findings
    • Rugger jersey spine in hyperparathyroidism
    • Brown tumors in hyperparathyroidism
    • Imaging in metabolic bone disease
    • Hypoparathyroidism
    • Pseudohypoparathyroidism
    • Brachydactyly in pseudohypoparathyroidism
    • Hypoparathyroidism family

    13 slides

  4. 04

    Pituitary and thyroid effects

    Pituitary hyperfunction, thyroid hyperfunction and thyroid hypofunction

    • Pituitary hyperfunction and bone growth
    • Gigantism versus acromegaly
    • Acromegaly on the skeleton
    • Spade tufts in acromegaly
    • Thyroid hyperfunction
    • Thyroid acropachy periostitis
    • Thyroid hypofunction

    7 slides

  5. 05

    Diffuse osteosclerosis (dense bones)

    Renal osteodystrophy through fluorosis — a short, high-yield differential

    • Osteosclerosis overview
    • Differential diagnosis of diffuse bony sclerosis
    • “
    • Differential of diffuse osteosclerosis (first five)
    • Differential of diffuse osteosclerosis (last five)
    • Renal osteodystrophy
    • Sickle cell disease
    • Fish vertebrae in sickle cell disease
    • Myelofibrosis
    • Myelofibrosis with splenomegaly
    • Osteopetrosis
    • Diffuse sclerosis in osteopetrosis
    • Sandwich vertebrae in osteopetrosis
    • Pyknodysostosis
    • Pointed sclerotic tufts in pyknodysostosis
    • Metastatic carcinoma
    • Mastocytosis
    • Mastocytosis bone density and bowel folds
    • Paget's disease
    • Paget's disease of the L3 vertebra
    • Paget's disease of the pelvis and femur
    • Paget's three phases
    • Paget's disease phases
    • Paget's disease of the tibia showing all three phases
    • Athletes
    • Fluorosis
    • Summary
    • Suggested readings
    • Brant and Helms' Fundamentals of Diagnostic Radiology

    29 slides