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Radiology

Endocrine Gland Scintigraphy

Built from Fundamentals of Diagnostic Radiology

What’s inside

8 sections · 108 slides

  1. 01

    Overview

    • Endocrine gland scintigraphy
    • What scintigraphy adds to endocrine workup

    2 slides

  2. 02

    Thyroid

    Imaging methods, radiopharmaceuticals, uptake, anatomy, and thyroid disease

    • Thyroid imaging methods
    • When thyroid scintigraphy is used
    • Thyroid radiopharmaceuticals
    • Radiopharmaceuticals used for thyroid imaging
    • Functional classes of a thyroid nodule
    • Hot, cold, and indeterminate nodules
    • Why 'warm' confuses clinicians
    • Discordant thyroid nodules
    • Radioactive iodine uptake (RAIU)
    • Three reasons to measure RAIU
    • How RAIU is measured
    • Radioactive iodine uptake formula
    • Thyroid embryology
    • Thyroid anatomy
    • Normal thyroid in cross-section and scan
    • Thyroid cells and hormone control
    • Thyroid hormone axis
    • Iodine handling
    • Hypothyroidism
    • Hyperthyroidism
    • Goiter
    • Multinodular goiter
    • Thyroid nodules on I-123 scan
    • Nontoxic goiter
    • Thyroiditis overview
    • Acute and subacute thyroiditis
    • Postpartum and Hashimoto thyroiditis
    • Riedel thyroiditis and secondary hyperthyroidism
    • Graves disease
    • Graves disease on I-123 scan
    • Treating Graves disease with I-131
    • How I-131 works
    • I-131 therapy sequence
    • I-131 dose formula
    • I-131 dose strategy
    • I-131 precautions
    • I-131 complications

    37 slides

  3. 03

    Thyroid Nodules

    How common they are, workup limits, and the differential diagnosis

    • Nodules are common, cancer is rare
    • Imaging limits in nodule workup
    • Nodule function and cancer risk
    • Follicular adenoma
    • Cold nodule: follicular adenoma
    • Adenomatous hyperplasia
    • Thyroid cysts
    • Hemorrhagic cysts
    • Hot nodules
    • Hot nodule on thyroid scan

    10 slides

  4. 04

    Thyroid Cancer

    Risk assessment, histologic types, imaging, and radioiodine therapy

    • Thyroid cancer burden
    • Assessing nodule malignancy risk
    • Signs suggesting benign etiology
    • Signs suggesting malignancy
    • Benign versus malignant clues
    • Papillary carcinoma
    • Follicular carcinoma
    • Medullary carcinoma
    • Anaplastic carcinoma
    • Thyroid cancer imaging after surgery
    • Reading a thyroid cancer scan
    • Thyroid cancer lymph-node metastasis
    • Follicular cancer pelvic metastasis with SPECT
    • Thyroid cancer recurrence with nodal metastases
    • SPECT-CT and FDG PET in thyroid cancer
    • Hurthle cell carcinoma
    • Postablation follow-up with rhTSH
    • Radioiodine therapy for thyroid cancer
    • I-131 dosing and preparation
    • I-131 side effects
    • Metastases to the thyroid

    21 slides

  5. 05

    Parathyroid

    Localizing adenomas, hyperplasia, and carcinoma in hyperparathyroidism

    • Parathyroid disorders and imaging role
    • Causes of hyperparathyroidism
    • Parathyroid localization methods
    • When localization is needed
    • Parathyroid adenoma on Tc-99m sestamibi SPECT-CT
    • Radionuclide subtraction imaging
    • Pitfalls of subtraction imaging
    • Subtraction imaging sequence
    • Parathyroid subtraction technique
    • Tc-99m sestamibi parathyroid imaging
    • Parathyroid adenoma on sestamibi planar scan
    • Parathyroid anatomy
    • Parathyroid adenomas and hyperplasia
    • Parathyroid carcinoma and ectopic glands

    14 slides

  6. 06

    Adrenal

    Functional imaging of adrenal medullary and neural crest tumors

    • Adrenal functional imaging
    • MIBG and adrenal medullary tumors
    • Adrenal tumor PET and therapy

    3 slides

  7. 07

    Neuroendocrine

    Imaging pheochromocytoma, paraganglioma, neuroblastoma, and carcinoid

    • Neuroendocrine tumor imaging
    • In-111 pentetreotide (Octreoscan)
    • Tumors imaged with In-111 pentetreotide
    • Carcinoid on In-111 pentetreotide planar scan
    • Insulinoma on In-111 pentetreotide SPECT-CT
    • I-123 MIBG for neuroendocrine tumors
    • I-123 MIBG scan in pediatric neuroblastoma
    • New PET tracers for neuroendocrine tumors
    • Endocrine gland scintigraphy: key takeaways

    9 slides

  8. 08

    References

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    • Brant and Helms' Fundamentals of Diagnostic Radiology

    12 slides