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Dermatology

Structure and Function of Eccrine, Apocrine, and Sebaceous Glands

Built from Dermatology, 5th Edition

What’s inside

4 sections · 63 slides

  1. 01

    Skin gland overview

    Three gland types built into the skin, and how they relate to hair follicles

    • Classification of skin exocrine glands
    • Shared features of the three gland types
    • Pilosebaceous unit anatomy
    • Comparing eccrine and apocrine glands
    • Characteristics of sweat glands

    5 slides

  2. 02

    Eccrine Sweat Glands

    Structure, nerve control, development, and disorders of the most widespread sweat gland

    • Key features of eccrine sweat glands
    • Eccrine gland distribution and density
    • Structure of the eccrine secretory coil
    • The eccrine duct and acrosyringium
    • Eccrine gland innervation
    • Embryonic development of eccrine glands
    • Composition of eccrine sweat
    • Two-step formation of eccrine sweat
    • Functions of eccrine sweat
    • Measuring sweat production
    • Methods for evaluating sweat production
    • Classification of sweat gland disorders
    • Hyperhidrosis: increased sweating
    • Complications of excess sweating
    • Hypohidrosis: reduced sweating
    • Drug-related eccrine disorders
    • Toxic erythema of chemotherapy on the hand
    • Mechanism of sweat retention (miliaria)
    • Miliaria types by depth of duct occlusion

    19 slides

  3. 03

    Apocrine Sweat Glands

    Where they sit, how they are built, and why their human function is unclear

    • Key features of apocrine sweat glands
    • Distribution of apocrine sweat glands
    • Structure of the apocrine secretory unit
    • Distinguishing apocrine from eccrine glands
    • Innervation of apocrine sweat glands
    • Comparing eccrine and apocrine innervation
    • Innervation and receptor profiles of sweat glands
    • Embryonic development of apocrine glands
    • Composition of apocrine sweat
    • Mechanisms of apocrine secretion
    • Possible functions of apocrine sweat
    • Bromhidrosis: apocrine body odor
    • Apocrine chromhidrosis

    13 slides

  4. 04

    Sebaceous Glands

    Structure, development, and their central role in acne vulgaris

    • Key features of sebaceous glands
    • Free sebaceous glands without a hair follicle
    • Three types of pilosebaceous units
    • Anatomic parts of a sebaceous follicle
    • Zones of the follicular infundibulum
    • Resident microorganisms of the sebaceous follicle
    • Sebaceous gland development
    • Stem cells and sebocyte differentiation
    • Holocrine secretion of sebum
    • Composition of sebum
    • Hormonal and neuropeptide regulation of sebum
    • Regulators of the sebaceous gland in acne and rosacea
    • Sebostasis and seborrhea
    • Androgen regulation of sebum and acne
    • Overview of acne vulgaris pathogenesis
    • Hormonal pathways in acne vulgaris pathogenesis
    • Six categories of sebaceous gland action in acne and rosacea
    • Roles of the sebaceous gland in acne and rosacea pathogenesis
    • C. acnes and free fatty acids in acne pathogenesis
    • External and drug triggers of acne-like eruptions
    • 1.5-4M
    • Summary
    • References
    • References (continued)
    • References (continued)
    • Dermatology, 5th Edition (2-Volume Set)

    26 slides