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Dermatology

Other Viral Diseases

Built from Dermatology, 5th Edition

What’s inside

16 sections · 172 slides

  1. 01

    Overview

    • What is a viral exanthem?
    • Relative size and shape of viruses that infect the skin
    • Nonspecific viral exanthems
    • Diagnostic approach to a morbilliform (measles-like) exanthem

    4 slides

  2. 02

    Enterovirus Infections

    Hand-foot-and-mouth disease, herpangina, and other exanthems

    • Enterovirus infections: key features
    • How enterovirus infection spreads in the body
    • Clinical manifestations of enterovirus infection
    • Hand-foot-and-mouth disease (HFMD)
    • Hand-foot-and-mouth disease, including the coxsackievirus A6 variant
    • Coxsackievirus A6 (CVA6): an atypical HFMD
    • Coxsackievirus A6 infection: additional presentations
    • Hand-foot-and-mouth disease: finger and palm involvement
    • Hand-foot-and-mouth disease: palmar vesicles
    • Coxsackievirus A6 infection: sole involvement in adults
    • Herpangina
    • Other enteroviral exanthems
    • Widespread non-blanching enteroviral exanthem
    • Diagnosis of enterovirus infection
    • Serologic assays of antibody responses
    • Treatment of enterovirus infection

    16 slides

  3. 03

    Measles

    Rubeola: a vaccine-preventable exanthem that still causes outbreaks

    • Measles: key features
    • Measles: prodrome and Koplik spots
    • Measles exanthem
    • Measles: cephalocaudad spread and complications
    • Atypical measles
    • Measles: treatment and prevention

    6 slides

  4. 04

    Rubella

    German measles: mild in most, dangerous for the unborn fetus

    • Rubella: key features
    • Rubella: clinical features
    • Rubella: joint and organ complications
    • Congenital rubella syndrome
    • Rubella virus persisting after immunodeficiency or vaccination
    • Rubella: treatment and prevention

    6 slides

  5. 05

    Erythema Infectiosum

    Fifth disease: parvovirus B19 and its many faces

    • Parvovirus B19: history and overview
    • Parvovirus B19: how it spreads and infects
    • Course of parvovirus B19 infection
    • Parvovirus B19: viremia, antibodies, and rash timing
    • Erythema infectiosum: the classic rash
    • Erythema infectiosum: slapped cheeks and the lacy eruption
    • Erythema infectiosum: the lacy pattern on the upper arm
    • Papular-purpuric gloves and socks syndrome (PPGSS)
    • Papular-purpuric gloves and socks syndrome
    • PPGSS: petechiae on the sole
    • Parvovirus B19: joint disease and fetal infection
    • Parvovirus B19 clinical associations
    • Parvovirus B19 clinical associations (continued)
    • Parvovirus B19: diagnosis and treatment

    14 slides

  6. 06

    Roseola Infantum

    Sixth disease: high fever in infants, rash after the fever breaks

    • Roseola infantum: key features
    • Roseola infantum: clinical course

    2 slides

  7. 07

    Unilateral Laterothoracic Exanthem

    A one-sided rash of unknown but likely viral cause

    • ULTE: key features and epidemiology
    • Unilateral laterothoracic exanthem
    • ULTE: cause, course, and differential diagnosis

    3 slides

  8. 08

    Gianotti-Crosti Syndrome

    A symmetric papular eruption triggered by many different viruses

    • Gianotti-Crosti syndrome: history and key features
    • Gianotti-Crosti syndrome
    • Gianotti-Crosti syndrome: facial involvement
    • Gianotti-Crosti syndrome: epidemiology and pathogenesis
    • Potential etiologies reported in association with Gianotti–Crosti syndrome
    • Potential etiologies reported in association with Gianotti–Crosti syndrome (continued)
    • Gianotti-Crosti syndrome: clinical features
    • Gianotti-Crosti syndrome: differential diagnosis and treatment

    8 slides

  9. 09

    Poxvirus Infections

    Smallpox, mpox, orf, and molluscum contagiosum

    • The poxvirus family
    • Smallpox: a lingering bioterrorism concern
    • Eight poxvirus infections of humans
    • Smallpox: poxvirus profile
    • Smallpox: poxvirus profile (continued)
    • Vaccinia: poxvirus profile
    • Vaccinia: poxvirus profile (continued)
    • Mpox (previously monkeypox): poxvirus profile
    • Mpox (previously monkeypox): poxvirus profile (continued)
    • Cowpox: poxvirus profile
    • Cowpox: poxvirus profile (continued)
    • Orf: poxvirus profile
    • Orf: poxvirus profile (continued)
    • Milker's nodules: poxvirus profile
    • Deer-associated parapoxvirus infection: poxvirus profile
    • Deer-associated parapoxvirus infection: poxvirus profile (continued)
    • Tanapox: poxvirus profile
    • Cutaneous reactions to smallpox (vaccinia) vaccination
    • Ulceration at a vaccinia vaccination site
    • Comparison of varicella/disseminated zoster to smallpox
    • Mpox (monkeypox): clinical picture
    • Clinical spectrum of mpox lesions
    • Histopathologic findings in mpox
    • Widespread mpox infection in a patient with atopic dermatitis
    • Orf, milker's nodules, cowpox, and tanapox
    • Orf: hand lesion and histology
    • Orf: vesiculopustule on the finger
    • Molluscum contagiosum: the last poxvirus of humans
    • Molluscum contagiosum: lesions, dermatitis, and histology
    • Molluscum contagiosum: inflamed lesions and associated dermatitis
    • Molluscum contagiosum: numerous lesions with atopic dermatitis
    • Molluscum contagiosum: diagnosis and differential
    • Treatment of molluscum contagiosum
    • Treatment of molluscum contagiosum (continued)
    • Treatment of molluscum contagiosum (continued)
    • Molluscum contagiosum: newer treatments

    36 slides

  10. 10

    Viral Hemorrhagic Fevers, Including Dengue

    Zoonotic viral illnesses ranging from mild fever to life-threatening shock

    • Viral hemorrhagic fevers: overview
    • Eight viral hemorrhagic fevers compared
    • Lassa fever: epidemiologic profile
    • New World arenaviruses (Junin, Machupo, Guanarito, Sabia): epidemiologic profile
    • Ebola virus disease: epidemiologic profile
    • Marburg virus disease: epidemiologic profile
    • Hantavirus infection: epidemiologic profile
    • Crimean-Congo hemorrhagic fever: epidemiologic profile
    • Rift Valley fever: epidemiologic profile
    • Yellow fever: epidemiologic profile
    • Dengue: clinical features
    • Geographic distribution of dengue
    • Severe dengue: DHF and DSS
    • Dengue: diagnosis and vaccines

    14 slides

  11. 11

    West Nile, Zika, Chikungunya, and Related Viruses

    Mosquito-borne viral infections with distinctive skin signs

    • West Nile virus infection
    • Zika virus infection
    • Chikungunya fever
    • Barmah Forest and Ross River virus infections
    • Mosquito-borne viral infections compared

    5 slides

  12. 12

    Cutaneous Manifestations of Hepatitis A, B, and C

    Skin findings that can point to an underlying liver infection

    • Hepatitis viruses and the skin
    • Cutaneous manifestations of hepatitis B and/or C infection

    2 slides

  13. 13

    Polyomavirus Infections

    Trichodysplasia spinulosa and other skin disease from human polyomaviruses

    • Human polyomaviruses: an emerging group
    • Trichodysplasia spinulosa: clinical features
    • Cutaneous polyomavirus infections: spiny papules and HPyV6 spicules
    • Trichodysplasia spinulosa in a renal transplant recipient
    • Pruritic and dyskeratotic dermatoses (PDD)
    • HPyV7-associated pruritic dermatosis: skin biopsy findings
    • HPyV7-associated pruritic dermatosis: clinical appearance
    • Polyomavirus skin disease: treatment

    8 slides

  14. 14

    Rabies

    No skin rash, but dermatologists may be asked to biopsy nuchal skin

    • Rabies and the dermatologist's role
    • Pathogenesis of rabies infection

    2 slides

  15. 15

    Cutaneous Manifestations of SARS-CoV-2 Infection

    Skin findings of COVID-19 and its vaccines, plus MIS-C in children

    • SARS-CoV-2 infection: skin involvement overview
    • Cutaneous manifestations of SARS-CoV-2 infection and vaccination
    • Cutaneous manifestations of SARS-CoV-2 infection and vaccination (continued)
    • Cutaneous manifestations of SARS-CoV-2 infection and vaccination (continued)
    • Cutaneous manifestations of SARS-CoV-2 infection and vaccination (continued)
    • Urticaria associated with SARS-CoV-2 infection
    • Delayed local reaction ("COVID arm") to an mRNA vaccine
    • Multisystem inflammatory syndrome in children (MIS-C)
    • MIS-C: 2023 CDC diagnostic criteria
    • MIS-C: 2023 CDC diagnostic criteria (continued)
    • MIS-C: 2023 CDC diagnostic criteria (continued)
    • MIS-C versus Kawasaki disease
    • MIS-C versus Kawasaki disease (continued)
    • MIS-C versus Kawasaki disease (continued)

    14 slides

  16. 16

    Kawasaki Disease

    An acute febrile illness that can silently damage the coronary arteries

    • Kawasaki disease: history and importance
    • Kawasaki disease: epidemiology
    • Kawasaki disease: pathogenesis theories
    • Kawasaki disease: diagnostic criteria
    • Kawasaki disease: diagnosis requires the fever plus 4 of 5
    • Kawasaki disease: perineal, palmar, and truncal findings
    • Kawasaki disease: urticarial rash and chapped lips
    • Kawasaki disease: early clinical clues
    • Facial findings: Kawasaki disease versus staphylococcal scalded skin syndrome and erythema multiforme major
    • Kawasaki disease: conjunctival and oral findings
    • Kawasaki disease: cardiac and other organ involvement
    • Incomplete (atypical) Kawasaki disease
    • Kawasaki disease: first-line treatment
    • Kawasaki disease: refractory disease
    • Kawasaki disease: long-term outlook
    • Classic childhood exanthems: quick recall
    • Key take-home points
    • References
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    • Dermatology, 5th Edition (2-Volume Set)

    32 slides