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Dermatology
Other Papulosquamous Disorders
Built from Dermatology, 5th Edition
What’s inside
8 sections · 114 slides
Overview
- What this topic covers
Small Plaque Parapsoriasis
A chronic, usually benign patch disease once lumped under “parapsoriasis”
- The confusing history of “parapsoriasis”
- Key features of small plaque parapsoriasis
- Epidemiology of small plaque parapsoriasis
- Pathogenesis: what drives small plaque parapsoriasis
- Clinical features: patches and digitate dermatosis
- Digitate dermatosis on the flank
- Pathology of small plaque parapsoriasis
- Differential diagnosis
- Principal differential diagnosis of small plaque parapsoriasis and large plaque parapsoriasis / early stage mycosis fungoides
- Treatment of small plaque parapsoriasis
- Therapeutic ladder for small plaque parapsoriasis and large plaque parapsoriasis / early stage mycosis fungoides
Large Plaque Parapsoriasis
Patches that many experts now regard as an early stage of skin lymphoma
- Large plaque parapsoriasis and its link to lymphoma
- Large plaque parapsoriasis and retiform pattern
- Making the diagnosis of large plaque parapsoriasis
Pityriasis Lichenoides
A disease spectrum from acute crusted papules (PLEVA) to chronic scaly ones (PLC)
- Pityriasis lichenoides: one spectrum, two ends
- Epidemiology and pathogenesis
- Pityriasis lichenoides as a T-cell disorder
- Clinical spectrum, from PLEVA to PLC
- Febrile ulceronecrotic Mucha–Habermann disease (FUMHD)
- Ulceronecrotic PLEVA (FUMHD)
- Mixed PLEVA and PLC lesions
- Crusted and scaly papules in pityriasis lichenoides
- Widespread acute PLEVA
- Chronic pityriasis lichenoides (PLC)
- Chronic pityriasis lichenoides with hypopigmentation
- Chronic PLC papules
- Chronic PLC with hypopigmented macules
- Chronic PLC presenting with hypopigmentation
- Children versus adults
- Pathology of pityriasis lichenoides
- Lichenoid interface dermatitis on histology
- Differential diagnosis of pityriasis lichenoides
- Differential diagnosis of pityriasis lichenoides
- First-line treatment of pityriasis lichenoides
- Therapeutic ladder for pityriasis lichenoides
- Treating more severe disease
Pityriasis Rubra Pilaris
Orange-red scaly plaques with islands of sparing, in six clinical types
- History of pityriasis rubra pilaris
- Epidemiology and CARD14-related genetics
- What triggers pityriasis rubra pilaris
- Classic clinical features
- Orange-red palmar keratoderma in PRP
- Nail, scalp, and mucosal involvement
- Symptoms and PRP look-alike complications
- Six clinical types of pityriasis rubra pilaris
- Classification of pityriasis rubra pilaris
- Juvenile types III–V
- Circumscribed juvenile PRP (type IV)
- CARD14-associated papulosquamous eruption (CAPE)
- Type VI: HIV-associated pityriasis rubra pilaris
- Orange-red keratotic follicular papules
- Islands of sparing on the flanks
- Confluent orange-red plaques with sparing
- Orange-red palms with waxy keratoderma
- PRP-like presentation in juvenile dermatomyositis
- PRP erythroderma with palmar fissuring
- Pathology: the “checkerboard” pattern
- Distinguishing PRP from psoriasis
- Topical treatment of pityriasis rubra pilaris
- Systemic retinoids and methotrexate
- Biologics and other treatments
- Treating juvenile PRP
Pityriasis Rosea
A common, self-limited eruption of adolescents and young adults
- Introduction and history
- Epidemiology of pityriasis rosea
- Pathogenesis: the “paraviral” exanthem
- The herald patch
- Pityriasis rosea with a herald patch
- Herald patches vary across skin phototypes
- The generalized eruption
- Morphology and histology of a lesion
- Follicular pityriasis rosea in darker skin
- More clinical photographs: distribution and pattern
- Confluent pityriasis rosea on the trunk
- Papules and plaques of varying size
- Oval plaques with collarette scale
- Pityriasis rosea in darkly pigmented skin
- Two herald patches
- Fir-tree pattern of pityriasis rosea
- Collarette of white scale
- Lesions aligned along Langer cleavage lines
- Duration and symptoms
- Atypical (inverse) pityriasis rosea
- Inverse pityriasis rosea
- Inverse pityriasis rosea on the buttocks
- Differential diagnosis of pityriasis rosea
- Treatment of pityriasis rosea
Pityriasis Rotunda
Large circular scaly patches, mainly in the Far East, Mediterranean, and African-descent populations
- Overview and history
- Pityriasis rotunda
- Epidemiology and associations
- Hyperpigmented plaques of pityriasis rotunda
- Clinical features, classification, and pathology
- Differential diagnosis and treatment
Granular Parakeratosis
Keratotic papules and plaques in skin folds, most often the axilla of adult women
- Overview and history
- Granular parakeratosis of the axilla
- Epidemiology and pathogenesis
- Clinical features
- The infantile form
- Granular parakeratosis: axillary plaque
- Pathology: retained keratohyalin granules
- Granular parakeratosis: histopathologic findings
- Axillary granular parakeratosis histology
- Differential diagnosis and treatment
- Key takeaways, part 1
- Key takeaways, part 2
- References
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- Dermatology, 5th Edition (2-Volume Set)