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Dermatology
Deposition Diseases
Built from Dermatology, 5th Edition
What’s inside
6 sections · 75 slides
Overview
- What is a cutaneous deposition disease
- Five deposition diseases covered here
- Telling deposition diseases apart on biopsy
- Disorders with dermal deposits - histologic features
- Disorders with dermal deposits - histologic features (continued)
- Disorders with dermal deposits - histologic features (continued)
Gout
Urate crystal arthropathy - the most common crystal-induced arthritis
- What gout is
- Epidemiology of gout
- How uric acid builds up: overproduction vs under-excretion
- Classification of hyperuricemia
- From crystals to inflammation
- Four clinical stages of gout
- Acute gouty arthritis
- Chronic tophaceous gout
- Tophaceous gout of a digit
- Tophaceous gout of the tragus
- Gout pathology on biopsy
- Tophaceous gout - histopathologic features
- Staining the crystals
- Tophaceous gout - localized to extensive
- Tophaceous gout involving the ear
- Tophaceous gout - amorphous dermal deposits
- Tophaceous gout - needle-like clefts on higher magnification
- Differential diagnosis of gout
- Treating an acute gout attack
- Lowering uric acid long-term
- Allopurinol and febuxostat side effects
- Other gout treatments
Pseudogout
Calcium pyrophosphate dihydrate crystal disease
- What pseudogout is
- Pseudogout mechanism and symptoms
- Pseudogout - histopathologic features
- Gout vs pseudogout at a glance
- Treating pseudogout
Lipoid Proteinosis
Hyalinosis cutis et mucosae - Urbach-Wiethe disease
- What lipoid proteinosis is
- Who gets lipoid proteinosis
- ECM1: the gene behind lipoid proteinosis
- Three ECM1 protein isoforms
- Lipoid proteinosis: stage 1 (infancy)
- Lipoid proteinosis: stage 2 (skin thickening)
- Lipoid proteinosis - clinical features
- Beyond the skin: mouth, teeth, and brain
- Lipoid proteinosis on biopsy
- Lipoid proteinosis - biopsy findings
- Differential diagnosis of lipoid proteinosis
- Treating lipoid proteinosis
Colloid Milium
Colloid degeneration of sun-damaged skin
- What colloid milium is
- Who gets colloid milium and why
- What colloid milium looks like
- Juvenile and adult colloid milium
- Adult colloid milium on biopsy
- Adult colloid milium - biopsy findings
- Adult colloid milium - additional biopsy view
- Juvenile, pigmented, and nodular variants
- Differential diagnosis of colloid milium
- Treating colloid milium
Mucopolysaccharidoses
Inherited lysosomal enzyme deficiencies that let sugar chains build up
- What the mucopolysaccharidoses are
- Skin signs of MPS, and Hunter syndrome pebbling
- Dermal melanocytosis and hypertrichosis in Hunter syndrome
- Diagnosing MPS
- MPS findings on biopsy
- The mucopolysaccharidoses at a glance
- The mucopolysaccharidoses - enzyme, storage, and inheritance
- The mucopolysaccharidoses - enzyme, storage, and inheritance (continued)
- The mucopolysaccharidoses - enzyme, storage, and inheritance (continued)
- The mucopolysaccharidoses - organ involvement
- The mucopolysaccharidoses - organ involvement (continued)
- The mucopolysaccharidoses - organ involvement (continued)
- Treating the mucopolysaccharidoses
- Stem cell transplant and future therapies
- Key takeaways
- References
- References (continued)
- References (continued)
- References (continued)
- Dermatology, 5th Edition (2-Volume Set)