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Cardiology

Percutaneous Closure of Atrial Septal Defect and Patent Foramen Ovale

Built from Cardiovascular Catheterization and Intervention: A Textbook of Coronary, Peripheral, and Structural Heart Disease

What’s inside

7 sections · 95 slides

  1. 01

    Overview

    • Scope of this topic

    1 slide

  2. 02

    Atrial septal defect

    • Origins of transcatheter ASD closure
    • Formation of the interatrial septum
    • Septation sequence of the fetal atria
    • Fate of the foramen ovale after birth
    • Anatomical classification of atrial septal defects
    • Types of atrial septal defect
    • Anomalies associated with atrial septal defects
    • Ostium primum defect as a surgical lesion
    • Haemodynamic consequences of an atrial septal defect
    • Endocarditis prophylaxis in atrial septal defect
    • Indications for percutaneous ASD closure
    • Small defects without significant shunting
    • Closure decision in atrial septal defect
    • Fixed pulmonary hypertension and Eisenmenger physiology
    • Large defects with prolonged left-to-right shunting

    15 slides

  3. 03

    Devices and closure technique

    • Amplatzer septal occluder construction
    • Amplatzer septal occluder sizing and delivery
    • Amplatzer septal occluder
    • Amplatzer Cribriform occluder
    • Cribriform occluder for a fenestrated septum
    • Occlutech ASD occluder
    • Occlutech ASD occluder
    • Gore Cardioform septal occluder
    • Gore Cardioform septal occluder

    9 slides

  4. 04

    Performing the closure

    • Pre-procedural transoesophageal echocardiography
    • Deficient inferior rim
    • Anaesthesia and imaging guidance strategies
    • Access and anticoagulation
    • Exchange for a stiff wire
    • Balloon sizing of the defect
    • Balloon sizing of the atrial septal defect
    • Device selection and oversizing
    • Sheath introduction and air embolism prevention
    • Confirming device attachment before advancing
    • Deployment sequence of the double-disc device
    • Deployment sequence
    • Disc deployment on echocardiography and fluoroscopy
    • Closure with the Gore device
    • Post-procedural care and follow-up after ASD closure
    • Expected and late events after ASD closure

    16 slides

  5. 05

    Pitfalls and special situations

    • Balloon instability during sizing
    • Enlargement of the defect during the procedure
    • Device embolization
    • Snaring an embolized occluder in the pulmonary artery
    • Residual leak and device thrombus after ASD closure
    • Sinus venosus defects and atrial fibrillation
    • Iatrogenic atrial septal defect
    • Selective closure of iatrogenic defects

    8 slides

  6. 06

    Patent foramen ovale

    • Anatomy of the patent foramen ovale
    • Consequences of right-to-left shunting through a PFO
    • Paradoxical embolism through a patent foramen ovale
    • Conditions associated with patent foramen ovale
    • Anatomical categories of patent foramen ovale
    • Semi-quantitative grading of PFO shunt severity
    • Indications for PFO closure
    • Randomised trials of PFO closure for stroke prevention
    • Results of the randomised PFO closure trials
    • Establishing a diagnosis of PFO-related stroke
    • Risk scores for attributing stroke to the PFO
    • PFO closure for primary prevention
    • Migraine and patent foramen ovale
    • Randomised evidence for PFO closure in migraine
    • Selecting migraine patients for closure
    • Further potential considerations for PFO closure

    16 slides

  7. 07

    PFO devices and technique

    • Devices approved for PFO closure
    • Gore Cardioform occluder for PFO closure
    • Choosing between the two PFO devices
    • Amplatzer PFO occluder
    • Anaesthesia and imaging for PFO closure
    • Opening steps of PFO closure
    • Deploying the Amplatzer Talisman device
    • Deploying the Gore Cardioform device for PFO
    • Gore Cardioform closure sequence
    • Criteria for stable device position before release
    • Pacman sign of correct device seating
    • Post-procedural care after PFO closure
    • Difficult sheath advancement through the groin
    • Absent back-bleeding after wire removal
    • Residual leak on follow-up after PFO closure
    • Device thrombus on follow-up after PFO closure
    • Summary of ASD closure
    • Summary of PFO closure
    • References
    • References
    • References
    • References
    • Cardiovascular Catheterization and Intervention: A Textbook of Coronary, Peripheral, and Structural Heart Disease
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    24 slides